Growth is achieved by the term exposure.

Seo Houston is one of the critical part for the companies who are taking the steps to develop and grow to a flourishing outcome while making the use of the internet technologies. To do the promotion of the company over the internet has been the part of the competitive online promotion word, this is the need of every business enterprise and the people have to make them done for sure in order to have the things done in the right manner and deliver the result in the less time period.

Do people exactly know the reason why they have a need to have the search engine optimization done? I think no so let iomhouston have the chance to tell every individual the main concept which is behind this, exposure the most important thing which the person gets and helps in the increase of the sales which directly helps in increasing the revenue and once all these factors are been achieved and taken care of the growth the business automatically takes place. The very first thing to do is look on your website and make it in the way it actually attract the visitor.

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David Turbyfill-Choose the best doctor for your teeth

The smile is a precious thing to offer to others without any cost and we are willing to do anything to keep it in that way. There are some factors that affect our teeth and we have to make sure that we have taken every preventive measure against it. There are so many web pages that will help to do so. The davidturbyfill is one of them here there are expert opinions provided by one of the world known dentist Mr. David Turbyfill.

He has done so many articles that can be used for keeping our teeth in good shape. He is also an expert in pain free wisdom teeth removal. We can make appoint with him at any time and enjoy the misery of the wisdom teeth. Is usually comes between ages 18 and 35. Most people do not know about its consequences.The wisdom teeth can cause so many troubles to our lentil and physical health.The best way is to remove it at the right time and have a great time in life.The wisdom teeth can cause headaches, pain in the jay and after sometime it will be difficult for us to even chew our food.

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David Turbyfill-Choose the best doctor for your teeth

The smile is a precious thing to offer to others without any cost and we are willing to do anything to keep it in that way. There are some factors that affect our teeth and we have to make sure that we have taken every preventive measure against it. There are so many web pages that will help to do so. The davidturbyfill is one of them here there are expert opinions provided by one of the world known dentist Mr. David Turbyfill. He has done so many articles that can be used for keeping our teeth in good shape.

He is also an expert in pain free wisdom teeth removal. We can make appoint with him at any time and enjoy the misery of the wisdom teeth. Is usually comes between ages 18 and 35. Most people do not know about its consequences. The wisdom teeth can cause so many troubles to our lentil and physical health.

The best way is to remove it at the right time and have a great time in life. The wisdom teeth can cause headaches, pain in the jay and after sometime it will be difficult for us to even chew our food.

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Computer Software & Business Method

The proposed patent manual defines computer implemented invention as any invention the performance of which involves the use of computer, computer network or other programmable apparatus, or an invention one or more features which are realized wholly or partially by means of a computer programme/ programmes. Further, patent manual defines Computer programmes as a set of instructions for controlling a sequence of operations of a data processing system which closely resembles a mathematical method. Computer programme may be expressed in various forms e.g.,

Though proposed patent manual emphasises on disclosure of mode of operation for inventions involving apparatus and necessary sequence of steps for process related invention, yet it lays down categorically that a hardware implementation performing a novel function is not patentable if that particular hardware system is known or is obvious irrespective of the function performed. It manifests that for such kind of invention insertion of method steps in apparatus or some dependency shall be required to make them non-obvious.

The patent manual has also broadly categorised inventions related to computer/ computer programmes as below:

  • Method/process;
  • Apparatus/system; and
  • Computer program product

METHOD/PROCESS:

Further to make the invention patentable in India, the method claim should clearly define the steps involved in carrying out the invention and should have a technical character. In other words, it should solve a technical problem. The claims should incorporate the details regarding the mode of the implementation of the invention via. hardware or software, for better clarity. The claim orienting towards a “process/method” should contain a hardware or machine limitation. Technical applicability of the software claimed as a process or method claim, is required to be defined in relation with the particular hardware components. Thus, the “software per se” is differentiated from the software having its technical application in the industry.

Therefore, as per the patent manual, a claim directed to a technical process which process is carried out under the control of a programme (whether by means of hardware or software), cannot be regarded as relating to a computer programme as such. a series of verbal statements, a flowchart, an algorithm, or other coded form and maybe presented in a form suitable for direct entry into a particular computer, or may require transcription into a different format (computer language). It may merely be written on paper or recorded on some machine readable medium such as magnetic tape or disc or optically scanned record, or it maybe permanently recorded in a control store forming part of a computer.

 

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The Purpose of Method Flexibility

These are reasons to modify methods. We can improve accuracy and precision, we can get better method detection limits (MDL), we can compensate for interferences, we can increase throughput, we can use “green reagents” and we can encompass the analytical range actually needed. These things can be done, but only by modification of existing methods. There is not the time, nor the resources, to revalidate every single method after making minute changes. If we change a buffer reagent, for instance, why not just demonstrate that the new buffer performs equally, or better, than the old one?

The criterion of a 40CFR part 136.6-method modification is equivalency of results. In other words, do you get the same result before and after a modification? The point is, however, that these equivalent results are obtained on data of samples without interference. In a way we are comparing apples and oranges. We can’t just be creating more apples. We want our new method to perform better than the old one.

Proof of Equivalency

The most important aspect of method modification is that QC criteria are met. The QC must meet or exceed the criteria given in the approved method. If you obtain certain MDL’s and response factors with a 30-minute cycle time, do you obtain similar data when the time is shortened? If you reduce a volume from 500 ml to 50 ml, is the precision the same? Method flexibility gives us, for the first time in a long time, the opportunity to make those changes to methods that we know need to be changed. We can modify pH, or complex reagents, or buffers, and even some reagents for the purpose of getting better data. We can automate a manual method without getting a permission letter. 40 CFR part 136.6 should be viewed as a good thing.

To demonstrate equivalency, or illustrate what is different, the method generator prepares a two-column comparison between the approved method and the new one. For most items, such as scope, detector, and so forth the language will be the same. For method flexibility, the differences will be throughput, instrument, column, volumes of sample, and some of the reagents as long as 136.6 criteria is met.

Conclusion

In trace analysis, the analyte is present at very small quantities in relation to the rest of the sample matrix. It is literally looking for the needle in a haystack. A rapid chemical method looks for the needle without removing the hay. Lowering the MDL is similar to looking in even more hay for that one needle. At the same time, we want to find it faster, and with the least expense. Of course to use this analogy with accuracy and precision, or range we end up looking for multiple needles in the same haystack.

Method flexibility is needed because method developers cannot foresee every potential interference or anticipate all matrices in which the method might be applied. Blindly following a method that is not working strictly to stay “in compliance” defeats the purpose of the measurement-that is, to obtain the correct result, not just to follow the method. Remember, that not all instruments are the same. A method developed on one instrument may require slight modifications to work on another.

I believe that 40 CFR Part 136.6 method flexibility is the light at the end of the tunnel. Finally we are not bound to follow rigid SOP’s. You can alter your instruments and methodology so that you obtain accurate, reliable results in a cost effective manner. This is not about shortcuts. This is about being scientific, once again. The analysis is all about the data. It has to be defensible, but it also needs to be correct. I realize that the commercial laboratory is hard pressed with time and resources to do their own modifications.

 

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Method Flexibility

The methods are written including, not only the reagents needed to create a final measurable product, but also complex reagents and buffering reagents formulated to adjust pH and prevent interferences from occurring. It is impossible for one method, or one set of conditions to work on every matrix. Since wastewaters are so complex, wastewater methods must allow users to modify methodology to work on their samples. Rapid chemical methods, with as few steps as possible, are the only way thousands of samples can be analyzed by semiskilled or unskilled analysts. A rapid method performs well in the matrix it was tested assuming it is followed exactly.

So why do we have method flexibility? We have it because we asked for it. The ability to modify a method has been embedded in the QA/QC section of various methods and has gone under the ‘title’ of performance based for years. Later, method flexibility was added to 40 CFR as Part 136.6. Reasons to modify a method range from the change of one instrument to another to removal of matrix interferences.

Rapid Chemical Methods and Environmental Testing

Most countries have adopted rapid chemical methods for use in environmental regulations. The logic is that there is a maximum allowed limit for a toxin and we will measure it. Large sums of money are invested by industry and government agencies based on the numerical results of these methods. Because the methods are promulgated, the results whether right are wrong, determine compliance. Not following the SOP will place you out of compliance simply for not following the SOP word for word.

I have written numerous articles about total cyanide by distillation. It is possible to analyze total cyanide in a sample, get a positive result, get fined for releasing cyanide and cyanide not actually be there. A simple modification of the approved method reports the correct result, however, previously modification of the method was considered a violation even if the modification produced the correct result. In many cases following the SOP is OK, however, without modifying methods to handle as many interferences as possible you will never know.

Approval letters and the Alternative Test Procedure

The EPA ATP coordinator was overwhelmed with requests for approval of discrete analyzer methods. Previously, this so called approval occurred as approvals of powder pillows, and Flow Injection instead of Segmented Flow. Part 136.6 allows users and method generators to change methodology without EPA review or rule making, providing the minimum criteria is met. So why add method flexibility to the CFR? There are Alternative Test Procedures (ATP) that need to be properly evaluated so that these procedures can be promulgated. A method that simply modifies an approved method is not an ATP.

If you look closely at the wording of these “approval” letters, they are not approvals at all, but an acknowledgement by EPA the method in question is essentially equivalent to the approved one. EPA decided that the ATP coordinator’s time was better spent is pursuit of approving new alternative test procedures than it was with providing instrument manufacturers with letters to use as marketing material. The clincher of the deal was pretty much the discrete analyzer, which is essentially a new way to add reagents to samples and does not really change the methodology at all.

Another reason for method flexibility is the rigidity of the SOP. The earlier EPA methods were written under the assumption that chemists would use them. Over the years, as we are all aware, they became less used by chemists and more by lawyers. The mindset of following the SOP word for word developed and has reached a turning point. As we attempt to measure lower levels, we have to be able to adapt our current methods to allow us to see these lower levels. Not allowing a 25-milliliter purge volume because the method only says five milliliters, or not allowing capillary columns because the method calls for a packed column is silly and slows progress.

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